Wungki Park, MD, MS, is a gastrointestinal medical oncologist and physician-scientist at Memorial Sloan Kettering Cancer Center, where he leads the sPARK Lab and the GRIT (GI RAS Innovative Therapeutics) initiative. His work spans the clinical and translational development of novel RAS-directed therapeutics for pancreatic and other gastrointestinal cancers, from first-in-human studies of RAS(ON) inhibitors and targeted protein degraders to registrational trials in first-line metastatic and perioperative settings. His laboratory integrates tumor genomics, functional studies, and blood-based biomarkers to understand treatment response and resistance and develop new therapeutic combinations. Through GRIT, he brings these discoveries into clinical trials across gastrointestinal cancers. His work in earlier stages of disease aims to translate deeper responses into durable disease control and cure.