Paul is a surgical oncologist at the Odette Cancer Centre, University of Toronto. His primary focus is on cancer involving the liver, gallbladder, bile ducts, pancreas, and stomach. In particular, Paul treats many patients with cancer of the colon or rectum that have spread to the liver. Paul emphasizes maintenance or improvement in quality-of-life in the care of his patients in addition to cancer treatment.
Paul leads several clinical trials at Sunnybrook Health Sciences Centre and internationally, with the goal of improving the experience and outcomes of patients have surgery for cancer. He is the head of the HPB CONCEPT Team, a national collaborative group dedicated to advancing the care of patients having liver or pancreas surgery through multicenter clinical trials.

Paul is the surgical lead for the hepatic arterial infusion pump chemotherapy program at the Odette Cancer Centre. This is the only program of its kind in Canada and offers an additional therapeutic option for patients with colorectal liver metastases that can not be resected.

Paul obtained his medical degree and general surgical training at the University of Western Ontario, with a PhD in Health Research Methodology from McMaster University. He completed advanced fellowship training in complex surgical oncology at Memorial Sloan-Kettering Cancer Centre in New York prior to returning to his home of Toronto.